Table 2 Baseline characteristics of all included patients. ECOG: Eastern cooperative oncology group. Chromosomal abnormalities were categorised according to the Döhner hierarchical classification.
Variable | No. of patients (%) | |
|---|---|---|
n | 79 | |
Median age [IQR] (years) | 75 [70.5–79] | |
Sex | Male | 62 (78%) |
Female | 17 (22%) | |
ECOG performance score | 0–1 | 71 (90%) |
2–3 | 8 (10%) | |
Binet staging | A | 12 (15%) |
B | 25 (32%) | |
C | 42 (53%) | |
Chromosomal abnormalities | 17p deletion | 1 (1%) |
11p deletion | 11 (14%) | |
Trisomy 12 | 16 (20%) | |
13q deletion | 29 (37%) | |
No aberrations | 20 (25%) | |
Unknown | 2 (3%) | |
IGHV status | Mutated | 26 (33%) |
Unmutated | 34 (43%) | |
Unknown | 19 (24%) | |
Chemotherapy allocation | Bendamustine | 41 (52%) |
Chlorambucil | 38 (48%) | |
Allocation to idelalisib vs. placebo | Idelalisib | 35 (44%) |
Placebo | 44 (56%) | |
