Fig. 9 | Scientific Reports

Fig. 9

From: Antiarthritic activities of berberine in a rat model of gouty arthritis

Fig. 9

Effect of treatment on DNA fragmentation detected in knee cells of rats of different experimental groups: Negative control, Monosodium Urate (MSU)-induced arthritic rats, treated MSU + Berberine (BERB, 50 mg/kg/day, oral), treated MSU + Paracetamol (Para, 50 mg/kg/day, oral). (a) Results, as quantitative values of DNA fragmentation, are presented as mean ± SEM. Bars show mean and standard error at the group level with different letters (a, b, c, d) indicating statistical significance at P ≤ 0.05. (b) Qualitative values of DNA fragmentation in knee cells of arthritis rats. Lane M: DNA marker; Lane 1: Negative control rats, Lane 2: MSU-induced arthritic rats, Lane 3: treated MSU + BERB rats, and Lane 4: treated MSU + Para rats.

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