Table 3 DNA fragmentation detected in knee tissues of different treatment groups.

From: Antiarthritic activities of berberine in a rat model of gouty arthritis

Treatment

DNA Fragmentation %

Change

Inhibition %

Negative control

7.9 ± 0.56c

0

0.0

MSU arthritic rats

30.8 ± 0.93a

22.9

0.0

MSU + BERB

19.6 ± 0.45b

11.7

48.91

MSU + Para

21.5 ± 0.76b

13.6

40.61

  1. Groups: Negative control, Monosodium Urate (MSU)-induced arthritic rats, treated MSU + Berberine (BERB, 50 mg/kg/day, oral), treated MSU + Paracetamol (Para, 50 mg/kg/day, oral). Results are presented as mean ± SEM. Means with different superscripts (a, b, c) between treatments in the same column are significantly different at P < 0.05.