Fig. 3

Weighted gene expression co-expression network analysis (WGCNA) of 32,004 genes in the amniotic membrane during ascending placentitis and the identified 37 color-coded modules. Module-trait heatmap based on the relationships between co-expression modules and score traits (Inflammation and Placentitis). The “brown” module was positively correlated with inflammation and placentitis. The “dark magenta” module was negatively correlated with inflammation and placentitis. Each row represents the identified co-expression modules, and each column represents a specific trait. The color yellow indicates a positive correlation between the module and the trait, while the purple color indicates a negative correlation.