Fig. 4

GO and KEGG enrichment analysis of PRR-related DEGs.(a) Bubble plot showing Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment results for PRR-related DEGs. Terms from the biological process (BP), molecular function (MF), and KEGG pathways are shown on the x-axis. Bubble size reflects the number of enriched genes, and bubble color indicates the p-value (orange = lower p-value; blue = higher p-value).(b–d) Network diagrams of enriched terms: (b) BP, (c) MF, and (d) KEGG. Orange nodes represent GO/KEGG terms, blue nodes represent genes, and edges indicate gene-term associations.Enrichment significance was defined as p-value < 0.05 and FDR (q-value) < 0.25.GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; BP, Biological Process; MF, Molecular Function.