Fig. 5 | Scientific Reports

Fig. 5

From: Study on differentially expressed genes and pattern recognition receptors in osteoporosis based on bioinformatics analysis

Fig. 5

Protein–protein interaction (PPI) network and hub gene identification.(a) PPI network of PRR-related DEGs constructed using the STRING database. (b–f) PPI subnetworks of the top 10 genes ranked by five different algorithms in the CytoHubba plugin: (b) Maximal Clique Centrality (MCC), (c) Maximum Neighborhood Component (MNC), (d) Degree, (e) Edge Percolated Component (EPC), and (f) Closeness. (g) Venn diagram showing the overlap of the top 10 genes identified by all five algorithms.PPI, protein–protein interaction; DEGs, differentially expressed genes; PRR, pattern recognition receptor.

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