Table 3 Molecular dynamics results of the best 2 shortlisted SiRNAs (siRNA8, siRNA12) targeting GPR10 mRNA.

From: Molecular dynamics simulations based siRNA design against GPR10 reveals stable RNAi therapeutics for hormone-dependent uterine fibroids

siRNA name

mRNA target position

Average RMSD (nm)

Average RMSF (nm)

Average Potential Energy (kJ/mol)

Average Radius of Gyration (nm)

siRNA8

2031–2053

0.460142016

0.221563902

−2191432.758

3.169483187

siRNA12

3722–3744

0.402216039

0.190397079

−2078929.49

3.07525014

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