Fig. 3 | Scientific Reports

Fig. 3

From: Epitope mapping strategies for immunogenicity mitigation in streptokinase therapeutics: an in-silico study

Fig. 3

Predicted Conformational B-Cell Epitopes on the 3D Structure of Streptokinase. This figure depicts the 3D structure of the Streptokinase (SK) protein, with the protein backbone shown as a grey surface with a ribbon representation. The areas highlighted in hot pink represent the predicted conformational B-cell epitopes, which have the potential for antibody binding. These epitopes were identified using multiple in silico prediction tools including DiscoTope2.0, Ellipro, and EPSVR servers. The spatial distribution of these epitopes across the protein structure can be visualized, which reveals their complex three-dimensional arrangement. This image was generated using PyMOL version 3.0.0.

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