Fig. 1
From: Histamine as a mediator of cross-talk between human lung mast cells and macrophages
Effects of histamine on cytokine release from human lung macrophages (HLMs). HLMs (106 cells/well) were incubated (18 h at 37 °C) with complete medium (CTR), increasing concentrations of histamine (10−6−10−4 M) or LPS (1 µg/mL). IL-6 (A), TNF-α (B), and IL-1β (C) concentrations in supernatants were evaluated by ELISA and expressed as ng of mediators for mg of total proteins. Data are the mean ± SD of six independent experiments obtained from different donors. * p < 0.05; ** p < 0.01; *** p < 0.001 vs. CTR.
