Table 1 Comparison of demographic, cognitive, and clinical variables between participants with and without CSF biomarker data.

Age (mean ± SD)

74.49 ± 9.19 years

68.73 ± 7.06 years

p < 0.001*

Sex (female, N, %)

92 (50.8%)

49 (51%)

p = 0.973

Education years

10.01 ± 3.90

8.04 ± 4.13

p = 0.432

CAIDE score

7.54 +/- 1.99

8.01 ± 2.08

p = 0.947

Syndromic diagnoses (Number of subjects, % inside category)

CU 128 (70.7%)

SCD 16 (8.8%)

MCI 31 (17.1%)

DEM 6 (3.3%)

CU 58 (60.4%)

SCD 3 (3.1%)

MCI 16 (16.7%)

DEM 19 (19.8%)

p < 0.001*

SBP (mean ± SD)

147.11 ± 20.21 mmHg

150.28 ± 22.26 mmHg

p = 0.512

DBP (mean ± SD)

82.36 ± 8.77 mmHg

82.64 ± 12.24 mmHg

p = 0.095

MBP (mean ± SD)

108.08 ± 37.09 mmHg

106.77 ± 14.26 mmHg

p = 0.616

Cholesterol total (mean ± SD)

207.75 ± 36.96 mg/dL

211.98 ± 38.39

p = 0.762

Glucose (mean ± SD)

106.75 ± 29.34 mg/dL

106.33 ± 19.28 mg/dL

p = 0.228

BMI (mean ± SD)

27.49 ± 4.68 kg/m²

26.91 ± 3.98

p = 0.954

AD8 (mean ± SD)

0.82 ± 1.50

2.09 ± 2.69

p < 0.001*

Fototest (mean +/- SD)

37.33 ± 5.61

33.45 +/- 7.82

p = 0.006*

MMSE (mean ± SD)

27.13 ± 2.82

25.99 ± 4.19

p < 0.001*

M@T (mean ± SD)

43 ± 6.69

38.98 ± 10.05

p < 0.001*

Pfeiffer (mean ± SD)

1.03 ± 4.04

1.67 ± 5.51

p = 0.024*

HADS anxiety score (mean ± SD)

5.15 ± 3.07

4.41 ± 3.48

p = 0.013*

HADS depression score (mean ± SD)

3.03 +/- 2.83

3.21 +/- 2.95

p = 0.465

NPI total score (mean +/- SD)

2.74 +/- 7.39

3.52 +/- 9.62

p = 0.162