Fig. 3 | Scientific Reports

Fig. 3

From: Peroxiredoxins as novel indicators in multiple myeloma associated with ferroptosis and immune infiltration

Fig. 3

Function of PRDXs in multiple myeloma. Lollipop charts showing the functional and pathways enrichment analyses of (A) PRDX1, (B) PRDX2 and (C) PRDX6. GSEAs identifying the signaling pathways associated with (D) PRDX1 and (E) PRDX2. The relationship of PRDX1 to ferroptosis (F) inducers and (G) inhibitors was analysed separately in the GSE24080. TCGA-MMRF was used to analyse the correlation between PRDX2 and ferroptosis (H) inducers and (I) inhibitors. (J) The lollipop plots show the relationship between PRDXs mRNA levels and immune cell infiltration in the GSE276561. (K) Differential expression of chemokines, cytokines, and immunosuppressive factors between high- and low-expression groups. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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