Table 2 Comparison of baseline clinical and laboratory characteristics between patients with LA and control subjects.

From: Myelin basic protein and occludin may be the biomarkers to diagnose leukoaraiosis and cognitive dysfunction

Variable

Total (n = 198)

Control Group (n = 99)

LA Group (n = 99)

p-value

Mean ± SD

Median [Q1, Q3]

Mean ± SD

Median [Q1, Q3]

Mean ± SD

Median [Q1, Q3]

 

Age, years

68.15 ± 13.64

67.00 [61.00, 77.00]

66.73 ± 13.89

65.00 [58.50, 75.00]

69.57 ± 13.23

70.00 [63.00, 79.00]

0.117

MSBP, mmHg

129.85 ± 18.72

130.00 [120.00, 139.25]

125.94 ± 19.94

128.00 [118.00, 135.00]

133.76 ± 16.86

135.00 [125.00, 143.00]

0.003

MDBP, mmHg

73.75 ± 10.92

72.50 [66.00, 80.00]

70.75 ± 8.02

70.00 [65.00, 75.00]

76.75 ± 12.53

75.00 [68.00, 85.00]

< 0.001

FBG, mmol/L

5.95 ± 1.29

5.80 [5.10, 6.60]

5.68 ± 1.13

5.65 [4.93, 6.30]

6.22 ± 1.40

6.00 [5.33, 6.90]

0.005

2hPG, mmol/L

8.14 ± 2.67

7.60 [6.56, 9.10]

7.99 ± 2.92

7.36 [6.50, 8.60]

8.29 ± 2.38

7.80 [6.60, 9.60]

0.38

HbA1c, %

6.39 ± 1.06

6.18 [5.63, 6.86]

6.26 ± 0.97

6.00 [5.63, 6.36]

6.52 ± 1.13

6.30 [5.80, 6.90]

0.049

TC, mmol/L

3.24 ± 1.50

3.12 [2.35, 4.00]

2.98 ± 1.79

2.78 [1.66, 3.97]

3.51 ± 1.04

3.45 [2.89, 4.00]

0.009

TG, mmol/L

2.95 ± 1.51

2.89 [1.89, 3.78]

3.54 ± 1.23

3.56 [2.89, 4.13]

2.36 ± 1.53

1.98 [1.28, 3.23]

< 0.001

HDL-C, mmol/L

1.21 ± 0.60

1.13 [0.74, 1.52]

1.21 ± 0.58

1.16 [0.74, 1.52]

1.22 ± 0.62

1.11 [0.81, 1.49]

0.985

LDL-C, mmol/L

2.24 ± 0.69

2.20 [1.76, 2.69]

2.39 ± 0.62

2.35 [2.01, 2.78]

2.09 ± 0.72

2.01 [1.63, 2.47]

< 0.001

Hcy, µmol/L

11.60 ± 6.43

10.20 [7.80, 14.60]

8.73 ± 3.83

7.80 [6.30, 10.35]

14.47 ± 7.14

13.00 [9.90, 17.90]

< 0.001

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