Table 4 Generalized estimating equations (GEE) analysis for predictors of live birth, clinical pregnancy, positive pregnancy test, and early pregnancy loss (adjusted odds ratios).

Outcome	Predictor	aOR (95%CI)	p-value
Live birth rate (LBR)	Day 5 vs. Day 6 of progesterone	1.33 (0.83–2.14)	0.230 (NS)
	Age (years)	0.95 (0.91–0.99)	0.014*
	BMI (kg/m²)	0.98 (0.93–1.03)	0.545 (NS)
	EMT ≥ 7 mm vs. < 7 mm	1.39 (0.61–3.14)	0.435 (NS)
	Good-quality blastocyst	2.94 (1.63–5.31)	< 0.001**
Biochemical pregnancy rate (PR)	Day 5 vs. Day 6 of progesterone	1.30 (0.79–2.12)	0.305 (NS)
	Age (years)	0.97 (0.93–1.01)	0.106 (NS)
	BMI (kg/m²)	0.98 (0.93–1.03)	0.547 (NS)
	EMT ≥ 7 mm vs. < 7 mm	0.89 (0.39–2.01)	0.787 (NS)
	Good-quality blastocyst	2.34 (1.31–4.19)	0.003**
Clinical pregnancy rate (CPR)	Day 5 vs. Day 6 of progesterone	1.39 (0.82–2.34)	0.158 (NS)
	Age (years)	0.97 (0.93–1.00)	0.108 (NS)
	BMI (kg/m²)	0.99 (0.94–1.04)	0.685 (NS)
	EMT ≥ 7 mm vs. < 7 mm	1.01 (0.45–2.29)	0.99 (NS)
	Good-quality blastocyst	3.08 (1.67–5.66)	< 0.001**
Early pregnancy loss rate (EPLR)	Day 5 vs. Day 6 of progesterone	0.67 (0.34–1.32)	0.239 (NS)
	Age (years)	1.02 (0.97–1.08)	0.374 (NS)
	BMI (kg/m²)	1.02 (0.95–1.10)	0.639 (NS)
	EMT ≥ 7 mm vs. < 7 mm	0.65 (0.22–1.65)	0.434 (NS)
	Good-quality blastocyst	0.49 (0.23–1.10)	0.065 (NS)

All odds ratios are adjusted for the following covariates: maternal age (continuous), BMI (continuous), endometrial thickness (EMT, both continuous and dichotomized as ≥ 7 mm vs. <7 mm), and blastocyst quality (top-quality vs. lower-quality).
Abbreviations: aOR – adjusted odds ratio; CI – confidence interval; EMT – endometrial thickness; LBR – live birth rate; PR – positive pregnancy test rate; CPR – clinical pregnancy rate; EPLR – early pregnancy loss rate* – statistically significant; ** – highly statistically significant, NS – non significant.

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