Fig. 4

APOA1 was upregulated by DPM treatment in CCD-8Lu and Hs68 cells. CCD-8Lu and Hs68 cells were plated at a density of 4,000 cells/cm² in a 60 mm dish and incubated with various concentrations of DPM for 24–48 h at 70% confluence. (A) Cell viability determined by MTS assay after 24 h (B) The protein expression levels of APOA1 was determined by Western blot analysis. Each value is the mean ± SEM of three independent experiments. * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. 24 h control, † p < 0.05 and †† p < 0.01 vs. 48 h control. Unlabeled values were not statistically significant.