Table 2 Association of CD14 rs2569190 and rs2569191 polymorphisms with susceptibility to TB.
CD14 rs2569190 | Groups | OR (95% CI) | P-value | AIC | BIC | ||
|---|---|---|---|---|---|---|---|
Model | Genotype | Healthy control | TB patients | ||||
Allele | C | 368 (64.0%) | 276 (46.0%) | – | – | – | – |
T | 208 (36.0%) | 330 (54.0%) | – | – | – | – | |
Codominant | C/C | 104 (36.1%) | 48 (15.8%) | 1.00 | < 0.0001* | 752.1 | 769.7 |
C/T | 160 (55.6%) | 180 (59.4%) | 3.54 (2.29–5.45) | ||||
T/T | 24 (8.3%) | 75 (24.8%) | 18.58 (9.12–37.87) | ||||
Dominant | C/C | 104 (36.1%) | 48 (15.8%) | 1.00 | < 0.0001* | 785.8 | 799.0 |
C/T-T/T | 184 (63.9%) | 255 (84.2%) | 3.79 (2.46–5.82) | ||||
Recessive | C/C-C/T | 264 (91.7%) | 228 (75.2%) | 1.00 | < 0.0001* | 784.7 | 797.9 |
T/T | 24 (8.3%) | 75 (24.8%) | 5.65 (3.19–10.02) | ||||
Overdominant | C/C-T/T | 128 (44.4%) | 123 (40.6%) | 1.00 | 0.34 | 824.0 | 837.2 |
C/T | 160 (55.6%) | 180 (59.4%) | 1.17 (0.84–1.62) | ||||
Minor allele frequency (T) | 0.36 | 0.54 | – | – | – | – | |
CD14 rs2569191 | |||||||
|---|---|---|---|---|---|---|---|
Allele | G | 308 (53.0%) | 421 (69.0%) | – | – | – | – |
A | 268 (47.0%) | 185 (31.0%) | – | – | – | – | |
Codominant | G/G | 83 (28.8%) | 134 (44.2%) | 1.00 | < 0.0001* | 753.6 | 771.1 |
G/A | 142 (49.3%) | 153 (50.5%) | 0.37 (0.25–0.57) | ||||
A/A | 63 (21.9%) | 16 (5.3%) | 0.04 (0.02–0.09) | ||||
Dominant | G/G | 83 (28.8%) | 134 (44.2%) | 1.00 | < 0.0001* | 802.8 | 815.9 |
G/A-A/A | 205 (71.2%) | 169 (55.8%) | 0.37 (0.25–0.57) | ||||
Recessive | G/G-G/A | 225 (78.1%) | 287 (94.7%) | 1.00 | < 0.0001* | 773.7 | 786.9 |
A/A | 63 (21.9%) | 16 (5.3%) | 0.11 (0.06–0.21) | ||||
Overdominant | G/G-A/A | 146 (50.7%) | 150 (49.5%) | 1.00 | 0.77 | 824.8 | 838.0 |
G/A | 142 (49.3%) | 153 (50.5%) | 1.05 (0.76–1.46) | ||||
Minor allele frequency (A) | 0.47 | 0.31 | – | – | – | – | |
