Table 3 Level of MDA and GSH and activity of Gpx enzyme in the untreated control and treated hepatic cancer Hep-G2 cells with doxorubicin and frankincense nano-emulsion.

From: Frankincense oil nanoemulsion induces selective cytotoxicity and over ROS-mediated oxidative stress and apoptotic DNA damage in Hep-G2 hepatic cancer cells

Treatment

Concentration

MDA level (mmol/ml)

GSH level (mg/dL)

Gpx activity (mU/ml)

Untreated cells

0.00

1.61 ± 0.08 a

7.25 ± 0.52 a

55.94 ± 2.13 a

Doxorubicin

2 µM

3.13 ± 0.41 b

5.80 ± 0.56 b

45.73 ± 3.72 b

Frankincense nano-emulsion

44.03 µg/ml

5.37 ± 0.31 c

4.79 ± 0.34 c

37.06 ± 1.93 c

88.07 µg/ml

6.91 ± 0.35 d

3.92 ± 0.20 d

28.21 ± 2.53 d

176.14 µg/ml

8.21 ± 0.32 e

2.69 ± 0.42 e

15.09 ± 2.48 e

ANOVA

F = 218.53 p < 0.001

F = 49.20 p < 0.001

F = 110.85 p < 0.001

  1. Results are expressed as mean ± SD.
  2. Results were analyzed using one-way analysis of variance followed by Duncan’s test to test the similarity between the control and treated Hep-G2 cancer cells.
  3. Means with different letters indicates statistical significant difference at p < 0.001 between the compared cells in the same column.
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