Table 1 Spearman correlation between vandetanib-induced log2FC in Cal62 (at all three tested doses) and mean LINCS Z-scores (10 µM, 24 h) across all cell lines for the eight biomarker candidates.

From: Extracellular vesicle-associated transcriptomic and proteomic biomarkers show in vitro potential for vandetanib treatment monitoring in anaplastic thyroid cancer

Comparison

Spearman ‘s rho

p-value

Actinomycin D vs vandetanib EC10

-0.19

0.6646

Actinomycin D vs vandetanib EC50

0.29

0.5008

Actinomycin D vs vandetanib EC80

0.14

0.7520

Doxorubicin vs vandetanib EC10

0.07

0.8820

Doxorubicin vs vandetanib EC50

0.43

0.2992

Doxorubicin vs vandetanib EC80

0.29

0.5008

Mitomycin C vs vandetanib EC10

0.55

0.1710

Mitomycin C vs vandetanib EC50

0.83

0.0154

Mitomycin C vs vandetanib EC80

0.69

0.0694

Back to article page