Table 2 Results of GO and KEGG enrichment analysis for GRDEGs.

From: Role of glycolysis related genes in the pathogenesis of hemorrhoids and immune cell infiltration analysis

Ontology

ID

Description

GeneRatio

BgRatio

p-value

p.adjust

BP

GO:0006090

pyruvate metabolic process

13/34

106/18,800

2.29e−21

2.7e−18

BP

GO:0005996

monosaccharide metabolic process

15/34

261/18,800

1.34e−19

7.94e−17

BP

GO:0019318

hexose metabolic process

14/34

242/18,800

2.6e−18

1.03e−15

BP

GO:0006006

glucose metabolic process

12/34

201/18,800

7.15e−16

2.11e−13

BP

GO:0006096

glycolytic process

9/34

81/18,800

1.56e−14

3.44e−12

CC

GO:1,904,813

ficolin-1-rich granule lumen

4/34

124/19,594

6.12e−05

0.0070

CC

GO:0031983

vesicle lumen

5/34

327/19,594

0.0002

0.0110

CC

GO:0101002

ficolin-1-rich granule

4/34

185/19,594

0.0003

0.0110

CC

GO:0005635

nuclear envelope

5/34

479/19,594

0.0013

0.0381

CC

GO:0031965

nuclear membrane

4/34

300/19,594

0.0017

0.0382

MF

GO:0048029

monosaccharide binding

6/34

71/18,410

3.27e−09

4.95e−07

MF

GO:0019200

carbohydrate kinase activity

4/34

21/18,410

5.67e−08

4.28e−06

MF

GO:0000287

magnesium ion binding

6/34

222/18,410

2.91e−06

0.0001

MF

GO:0030246

carbohydrate binding

6/34

270/18,410

8.97e−06

0.0003

MF

GO:0016830

carbon-carbon lyase activity

3/34

50/18,410

0.0001

0.0030

KEGG

hsa00010

Glycolysis / Gluconeogenesis

10/34

67/8164

7.74e−14

1.17e−11

KEGG

hsa04922

Glucagon signaling pathway

11/34

107/8164

2.58e−13

1.95e−11

KEGG

hsa05230

Central carbon metabolism in cancer

8/34

70/8164

2.95e−10

1.48e−08

KEGG

hsa01200

Carbon metabolism

9/34

115/8164

6.22e−10

2.35e−08

KEGG

hsa04152

AMPK signaling pathway

8/34

121/8164

2.43e−08

7.33e−07

  1. GO, Gene Ontology; BP, Biological Process; CC, Cellular Component; MF, Molecular Function; KEGG, Kyoto Encyclopedia of Genes and Genomes; GRDEGs, Glycolysis-Related Differentially Expressed Genes.