Table 3 Number of signals and ROR for Con-DOX and Lip-DOX at the SMQ level in FAERS. (ROR, reporting odds ratio; Con-DOX, conventional doxorubicin; Lip-DOX, Liposomal doxorubicin; SMQ, standardized medical queries; 95% CI, 95% confidence interval).

From: FAERS based disproportionality analysis and network pharmacology investigation of doxorubicin associated drug induced cardiotoxicity

SMQ code

Con-DOX

Lip-DOX

Case, n

ROR

95% CI

Case, n

ROR

95% CI

20,000,150

355

34.07

30.64—37.88

240

18.39

16.18—20.90

20,000,004

278

5.88

5.22—6.63

223

3.80

3.33—4.34

20,000,067

93

2.29

1.87—2.81

56

1.12

0.86—1.45

20,000,057

53

2.24

1.71—2.93

34

1.16

0.83 −1.63

20,000,047

41

0.64

0.44—0.92

30

0.54

0.37—0.77

20,000,168

33

1.26

0.87—1.84

23

0.87

0.58—1.32

20,000,162

33

3.08

2.27—4.18

18

1.10

0.69—1.74

20,000,058

32

3.61

2.57—5.09

17

1.51

0.94—2.43

20,000,001

29

2.91

2.05—4.11

13

0.96

0.56—1.65

20,000,068

27

2.34

1.66—3.30

13

0.75

0.43—1.29

20,000,239

13

2.63

1.52—4.53

6

0.98

0.44—2.19

20,000,051

3

3.65

1.18—11.31

2

1.97

0.49—7.90