Table 2 Independent associations of dHU with poor outcomes.

From: Quantification of hounsfield unit difference in heterogeneous hematoma predicts poor functional outcomes in acute intracerebral hemorrhage

Characteristics

Secondary neurological

deterioration within 48 h

Poor 3-month mRS score

OR

95%CI

P-value

OR

95%CI

P-value

Age

1.001

0.979–1.023

0.953

1.011

0.991–1.031

0.301

Gender

1.109

0.580–2.120

0.754

1.345

0.746–2.426

0.325

Hypertension

1.116

0.628–1.984

0.708

1.330

0.790–2.240

0.283

Diabetes mellitus

0.661

0.252–1.731

0.399

1.273

0.490–3.304

0.620

SBP

1.015

1.004–1.026

0.006

1.009

1.000–1.018

0.063

DBP

1.025

1.009–1.041

0.002

1.015

1.002–1.028

0.028

Clinical/radiographic status at admission

Time from onset to baseline CT

0.998

0.997–1.001

0.513

0.997

0.989–1.004

0.375

Time from baseline CT to follow-up CT

0.820

0.512–1.300

0.397

0.859

0.483–1.527

0.601

GCS on admission

0.812

0.716–0.920

0.001

0.620

0.752–0.924

0.001

Hematoma volume

1.093

1.063–1.125

0.000

1.037

1.020–1.055

0.000

Laboratory testing

WBC

1.071

0.990–1.159

0.087

1.078

1.006–1.156

0.032

RBC

1.157

0.776–1.723

0.474

1.014

0.711–1.447

0.937

Hb

1.004

0.989–1.019

0.596

1.002

0.988–1.015

0.795

Platelet count

0.999

0.995–1.003

0.734

0.998

0.995–1.002

0.431

APTT

0.941

0.884–1.002

0.056

0.996

0.941–1.053

0.883

INR

0.389

0.039–3.862

0.420

2.584

0.973–1.033

0.142

PT

0.420

0.757–1.146

0.500

0.976

0.920–1.035

0.417

Fibrinogen

1.373

0.951–1.982

0.090

1.058

0.884–1.268

0.538

Radiographic status

Deep

0.713

0.479–1.035

0.094

1.136

0.942–2.590

0.084

Lobar

1.065

0.188–6.027

0.943

0.295

0.570–1.529

0.146

Infratentorial

1.816

0.136–4.890

0.824

0.220

0.038–1.270

0.090

Baseline CT, mean HU

Whole hematoma

0.955

0.904–1.008

0.096

0.950

0.904–0.998

0.042

hypo-area

0.973

0.935–1.012

0.172

0.990

0.955–1.025

0.561

hyper-area

0.958

0.905–1.013

0.131

0.912

0.864–0.962

0.001

Difference between hypo

and hyper area

1.007

0.966–1.050

0.741

0.963

0.927–1.000

0.053

Follow-up CT, mean HU

whole hematoma

1.074

1.024–1.127

0.003

1.024

0.983–1.067

0.258

hypo-area

1.034

1.001–1.069

0.051

1.016

0.986–1.046

0.304

hyper-area

1.097

1.040–1.156

0.001

1.021

0.977–1.067

0.364

Difference between hypo and hyper area

1.008

0.972–1.046

0.653

0.992

0.960–1.025

0.637

dHU

1.111

1.056–1.168

0.000

1.059

1.016–1.104

0.007

Multivariate analysis

Hematoma volume

1.090

1.057–1.123

0.000

1.019

1.001–1.037

0.040

GCS

0.832

0.711–0.974

0.022

0.784

0.682–0.901

0.001

SBP

1.004

0.986–1.021

0.669

-

-

-

DBP

1.017

0.991–1.044

0.196

1.017

1.000–1.035

0.053

HU of whole hematoma (initial CT)

-

-

-

1.118

1.012–1.234

0.028

HU of hyper-area (initial CT)

-

-

-

0.839

0.756–0.930

0.001

HU of whole hematoma (follow-up CT)

0.948

0.856–1.049

0.298

-

-

-

HU of hyper-area (follow-up CT)

1.068

0.962–1.187

0.218

-

-

-

dHU

1.116

1.031–1.208

0.006

1.156

1.086–1.232

0.000

  1. GCS, Glasgow coma scale; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell count; RBC, red blood cell count; Hb, hemoglobin; APTT, Activated partial thromboplastin time; PT, prothrombin time; INR, international normalized ratio; Hounsfield unit, HU; dHU = difference of mean HU.