Table 8 Upregulated and downregulated expression patterns in AML.
Proteins | Regulation in AML | Biomarker Validation From TTD Database | Biomarker Validation From Literature Mining |
|---|---|---|---|
KIT | Upregulated | Diagnostic Biomarker (Acute Graft vs Host Disease) | |
FLT3 | Upregulated | Prognostic Biomarker (Acute Myeloid Leukemia) | |
STAT3 | Downregulated | Diagnostic Biomarker (Psoriatic arthritis) | |
PIK3CA | Upregulated | Not reported | Unavailable |
PIK3CB | Upregulated | Not reported | Unavailable |
PIK3CD | Upregulated | Not reported | Unavailable |
PIK3R1 | Upregulated | Not reported | Unavailable |
AKT1 | Upregulated | Not reported | Unavailable |
MAPK1 | Downregulated | Not reported | Unavailable |
NFKB1/ RELA | Upregulated | Diagnostic Biomarker (Breast cancer) | |
PIM1 | Downregulated | Not reported | Unavailable |
PIM2 | Downregulated | Not reported | Unavailable |
MPO | Upregulated | Diagnostic and Prognostic Biomarkers (Metabolic Disorders) |
