Table 3 Estimated fixed effects and random effects as well as error model parameters for the best fitting nonlinear model. Both fixed and random effects are estimated using the SAEM algorithm.

From: Comparing neutralizing antibody activity over time between naïve and convalesced COVID-19 vaccinated individuals

Parameter

Estimate

Std. Error

Fixed Effects Estimates

\(r_{10}\)

0.089

0.015

\(\beta _{11}\)

−3.670

1.100

\(\beta _{12}\)

−0.905

0.236

\(r_{20}\)

0.028

0.041

\(\beta _{21}\)

−5.860

8.070

\(\beta _{22}\)

1.760

1.490

\(r_{30}\)

0.002

0.001

\(\beta _{31}\)

−1.440

1.390

\(\beta _{32}\)

−0.862

1.110

\(r_{40}\)

0.010

0.002

\(\beta _{41}\)

−2.100

0.431

\(A_{00}\)

0.00003

0.002

\(\beta _{01}\)

16.500

72.500

Random Effects Estimates

\(\omega _{1}\)

0.345

0.089

\(\omega _{2}\)

0.611

0.215

\(\omega _{3}\)

0.323

4.460

\(\omega _{4}\)

0.675

0.207

\(\omega _{0}\)

3.630

1.320

Correlation Estimates

\(\rho _{r_2, r_1}\)

−0.260

0.473

\(\rho _{r_3, r_1}\)

0.662

10.500

\(\rho _{r_4, r_1}\)

−0.145

0.559

\(\rho _{r_3, r_2}\)

0.151

4.930

\(\rho _{r_4, r_2}\)

0.841

0.258

\(\rho _{r_4, r_3}\)

0.346

1.710

Model Error Estimates

a

0.348

0.0266

b

0.206

0.0263