Table 1 Baseline characteristics of the study cohort.

From: Trajectory of frailty and association with adverse outcomes in patients with end-stage kidney disease over the first year of dialysis

 

All (n = 293)

Haemodialysis (n = 191)

Peritoneal dialysis (n = 102)

p-value (haemodialysis vs. peritoneal dialysis)

Age at dialysis start (years); median (IQR)

68 (56–76)

68 (57–75)

67 (55–77)

p = 0.841

Male sex; n (%)

190 (64.9)

128 (67.0)

62 (60.8)

p = 0.2872

eGFR at dialysis initiation3; median (IQR)

6.3 (5.0–7.8)

6.4 (4.9–7.9)

6.0 (5.2–7.6)

p = 0.8191

Ethnicity ; n (%)

 White

163 (55.6)

111 (58.1)

53 (51)

p = 0.7882

 Black

44 (15)

26 (13.6)

18 (17.7)

 South Asian

30 (10.2)

18 (9.4)

12 (11.8)

 Other ethnic group

3 (1)

2 (1.1)

1 (0.9)

 Unknown

53 (18.1)

34 (17.8)

19 (18.6)

Primary renal disease; n (%)

 Cystic kidney disease

15 (5.1)

8 (4.2)

7 (6.9)

p = 0.2932

 Pyelonephritis/obstruction

17 (5.8)

12 (6.3)

5 (4.9)

 Glomerulonephritis

30 (10.2)

16 (8.4)

14 (13.7)

 Renovascular disease/ hypertension

36 (12.3)

20 (10.5)

16 (15.7)

 Diabetic kidney disease

138 (47.1)

94 (49.2)

44 (43.1)

 Other causes

57 (19.5)

41 (21.5)

16 (15.7)

Comorbidities; n (%)

 Diabetes mellitus

178 (60.8)

124 (65)

54 (52.9)

p = 0.0452

 Ischaemic heart disease/ left ventricular failure

81 (27.7)

57 (29.8)

24 (23.5)

p = 0.2502

 Stroke/ TIA

29 (9.9)

22 (11.5)

7 (6.9)

p = 0.2042

 Peripheral arterial disease

23 (7.9)

15 (7.9)

8 (7.8)

p = 0.9982

Charlson-comorbidity score; mean (SD)

3.9 (1.5)

4.0 (1.5)

3.8 (1.4)

p = 0.1734

Age-adjusted Charlson-comorbidity score; mean (SD)

6.1 (2.1)

6.2 (2.2)

5.8 (2.0)

p = 0.10954

Baseline frailty score; mean (SD)5

4.1 (1.5)

4.2 (1.5)

3.8 (1.5)

p = 0.10044

Time of baseline CFS recording (number of days prior to dialysis start); median (IQR)5

50 (25–112)

53 (25–113)

48.5 (27–84)

p = 0.5441

  1. 1 Kruskal Wallis p-value.
  2. 2 Chi-squared p-value.
  3. 3 Estimated glomerular filtration rate calculated using the CKD-Epi 2021 equation.
  4. 4 Unpaired t-test p-value.
  5. 5 n = 189 (104 missing values).