Fig. 2 | Scientific Reports

Fig. 2

From: Proinflammatory pathways contribute to the pathogenesis of Clostridioides difficile infection in a murine model using Spatial transcriptomics

Fig. 2

Cluster analysis heatmap displays gene expression in Clostridioides difficile-infected mice, comparing symptomatic and asymptomatic groups across superficial and deep layers of the intestine. This visualization distinguishes between significantly upregulated and downregulated genes pivotal to activated pathways in symptomatic mice (Lcn2, Dusp1, Cxcl2, S100a8, S100a9, Defa2, Gstm1, H3c2, H4c17, Cd74, and B2m). Colors range from red (high expression) to blue (low expression), indicating distinct expression profiles between the groups.

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