Fig. 2
From: Bovine milk exosomes influence transcriptome profiles and reduce cardiac fibrosis in a rat model
Bovine milk exosomes altered mRNA and lncRNA expression profile in ISO-induced cardiac fibrosis rats. (a) Circos plot showing genome-wide transcript distribution across all chromosomes. From inside to outside: PBS1, PBS2, PBS3, Exosomes1, Exosomes2, Exosomes3. (b, c) Heatmap of inter-sample correlation base on Pearson’s correlation coefficients. High intra-group correlation indicates consistency, while low intergroup correlation indicates divergence. (d) Summary of overall and differently expressedtranscripts (e, f) Volcano plot of DEMs and DELs. Vertical lines represent twofold change cufoffs. The horizontal line indicates P = 0.05; red dots denote upregulated genes and blue dots denote downregulated genes. (g, h) Hierarchical clustering of DEMs and DELs. The color scale log10FPKM, with green indicating downregulation and red indicating upregulation.
