Fig. 6
From: Bovine milk exosomes influence transcriptome profiles and reduce cardiac fibrosis in a rat model
Co-expression network of DELs and their potential target mRNAs. (a) Circos plot showing chromosomal distribution of DEMs and DELs. The outer circle represents autosomes of the rat;  the second and third circles show DEMs, with red indicating upregulation and green indicating downregulation; column height represents the number of differentially expressed genes in that interval. The fourth and fifth circles show DELs with the same color coding. The inner circle indicates the top 500 co-expressing DEM–DEL pairs. (b) Co-expression network of DEL regulating mRNA in cis. (c) Co-expression network of DEL regulating mRNA in trans (red circles: DELs, green triangles: DEMs. (d) Transcription factor-target gene analyses network (red circle: DELs, green triangle: DEMs, yellow square: key transcription factors).
