Table 1 Detailed informationon the top 20 upregulated and top 20 down-regulated mRNAs.

From: Bovine milk exosomes influence transcriptome profiles and reduce cardiac fibrosis in a rat model

Gene name

Description

log2FC

p value

Upregulated

 LOC108348139

Class II histocompatibility antigen, M beta 1 chain

4.84

0.004

 Mis18a

MIS18 kinetochore protein A

4.03

0.021

 LOC102552169

Uncharacterized LOC102552169

3.50

0.014

 LOC100910130

Protein FAM50A-like

3.32

0.043

 Ciart

Circadian associated repressor of transcription

3.31

 < 0.001

 Cuzd1

CUB and zona pellucida-like domains 1

2.98

0.002

 Tmem200a

Transmembrane protein 200A

2.89

0.003

 Col1a2

Collagen type I alpha 2 chain

2.81

 < 0.001

 LOC100911237

Zinc finger protein 420-like

2.39

0.044

 RGD1560775

Similar to RIKEN cDNA 4930579C12 gene

2.22

0.005

 Lrrc73

Leucine rich repeat containing 73

2.17

0.018

 RGD1564247

Similar to SUMO/sentrin specific protease 5

2.15

0.028

 Mybl2

Myeloblastosis oncogene-like 2

2.07

0.007

 Dbp

D-box binding PAR bZIP transcription factor

2.06

 < 0.001

 Tonsl

Tonsoku-like, DNA repair protein

2.05

0.002

 LOC686087

Similar to motile sperm domain containing 1

1.98

0.009

 LOC102551694

Killin-like

1.92

0.002

 Hemgn

Hemogen

1.83

0.037

 Hk3

Hexokinase 3

1.75

 < 0.001

 Hmgb3

High mobility group box 3

1.74

 < 0.001

Downregulated

 Fat2

FAT atypical cadherin 2

− 3.16

0.033

 Cdcp1

CUB domain containing protein 1

− 3.09

0.025

 LOC103690039

Signal recognition particle subunit SRP68-like

− 2.96

0.024

 Ifitm6

Interferon induced transmembrane protein 6

− 2.82

0.003

 Acsbg1

Acyl-CoA synthetase bubblegum family member 1

− 2.82

0.004

 LOC103690118

Nuclear distribution protein nudE homolog 1-like

− 2.62

0.003

 Phykpl

5-Phosphohydroxy-L-lysine phospho-lyase

− 2.49

 < 0.001

 LOC100911733

Nuclear body protein SP140-like

− 2.47

0.002

 LOC108348048

von Willebrand factor A domain-containing protein 5A

− 2.46

0.021

 Pabpc5

Poly A binding protein, cytoplasmic 5

− 2.33

0.018

 LOC100912538

Centrin-3-like

− 2.30

0.036

 LOC100911769

Band 4.1-like protein 1-like

− 2.22

0.040

 LOC108350576

Zinc finger protein 120-like

− 2.04

 < 0.001

 Mcoln2

Mucolipin 2

− 1.98

0.024

 Ankef1

Ankyrin repeat and EF-hand domain containing 1

− 1.97

0.001

 Fos

FBJ osteosarcoma oncogene

− 1.89

0.000

 LOC103690914

Zinc finger protein 431-like

− 1.85

0.013

 Rnf212

Ring finger protein 212

− 1.67

0.042

 LOC100911238

Proteasome maturation protein-like

− 1.58

 < 0.001

 Cdkn2b

Cyclin-dependent kinase inhibitor 2B

− 1.52

0.018