Scheme 1

Synthetic route for TDA–Trz–POP via nucleophilic Substitution between cyanuric chloride and 2,5-dimercapto-1,3,4-thiadiazole under basic conditions in DMF.
Synthetic route for TDA–Trz–POP via nucleophilic Substitution between cyanuric chloride and 2,5-dimercapto-1,3,4-thiadiazole under basic conditions in DMF.