Fig. 4

Mesenchymal stem cell (MSC) implantation reduces radiation-induced fibrosis in the aorta.A, Representative images for Masson’s trichrome staining. Scale bars are as indicated. B and C, Quantitative analysis of fibrotic alterations for (B) intensity of alanine blue, and (C) IMT-HC. Mice were injected with MSCs or vehicle at 6 h after irradiation with 0–5 Gy, and the aorta was obtained for Masson’s trichrome staining at 4 weeks after irradiation. All data are presented as means ± SE (n = 8/group). p by Wilcoxon rank sum test (**, p < 0.01; *, 0.01 ≤ p < 0.05; ns, p ≥ 0.05, after Bonferroni corrections). AU, arbitrary unit.