Table 2 Cardiac contents of MDA, GSH and SOD in the studied groups.

From: Comparative study on the protective effect of dexrazoxane and blueberry extract against doxorubicin-induced cardiotoxicity in rats

Parameter

Control

DOX

BB

DEX

DOX + BB

DOX + DEX

BB + DOX + DEX

MDA (nmol/gm tissue)

3.06g

± 0.27

29.99a

± 1.80

3.41gfe

± 0.48

3.86ge

± 0.39

12.39b

± 0.83

10.21c

± 0.55

7.24d

± 0.55

GSH (µmol/gm tissue)

2.10ab

± 0.15

0.37g

± 0.10

2.16a

± 0.16

1.95c

± 0.10

1.45f

± 0.11

1.71e

± 0.07

1.94cd

± 0.09

SOD (U/mg protein)

31.93bc

± 1.85

6.83g

± 1.38

33.30ab

± 0.90

33.81a

± 2.18

16.50f

± 0.97

22.66e

± 1.03

26.82d

± 1.00

  1. Data are expressed as mean ± SD (n = 8). Groups are identified in the header row as follows: Control (g), DOX (f), BB (e), DEX (d), DOX + BB (c), DOX + DEX (b), and BB + DOX + DEX (a). Within each parameter row, superscript letters denote statistical significance: values sharing the same letter are not significantly different, while values with different letters differ significantly (p < 0.05, one-way ANOVA with Tukey’s post hoc test). A value carrying two letters (e.g., ef) indicates no significant difference from either group e or group f.
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