Fig. 4
From: Single-cell multi-omics uncovers CPS1 as a breast cancer immune evasion therapeutic target
High mitochondrial metabolism drives MIF-CXCR4 signaling-mediated immune escape. (A) Immune infiltration analysis based on the Cibersort algorithm in the TCGA-BRCA dataset. (B) Estimate algorithm to assess overall immune levels of samples. (C) CeE0771hat cell communication analysis of single-cell dataset with all differential ligand-receptor pairings demonstrated in high and low risk groups. (D) Strength of communication from tumor cells to T cells in risk subgroups. (E–F) Expression and prognostic roles of MIF signaling in the TCGA-BRCA dataset.
