Fig. 6

The effect of peptide 1 on mRNA expression levels measured by RT-PCR in zebrafish. Zebrafish larvae were treated with peptide 1 at concentrations of 50 and 200 µg/ml from 3 dpf to 6 dpf under high glucose conditions. mRNA levels of VEGF (A), Tie2 (B), and Angiopoietin-1 (C) were measured by RT-PCR. ####: p < 0.0001 vs. normal group. *, **, and ****: p < 0.05, p < 0.01, and p < 0.0001 vs. 130 mM glucose group.