Table 1 The rat’s liver lesion scoring of non-obese and obese rats with TRF.

From: The effects of time-restricted feeding on early vascular, liver, and renal structural changes, oxidative stress, and inflammation in obese rats

 

NOR

NOR+

TRFNC

OB

OB+

TRFHFD

OB+

TRFNC

Steatosis

     

Grade

0

0

1

0

0

Location

0

0

1

0

0

Microvesicular

0

0

1

0

0

Inflammation

     

Microgranulomas

0

0

0

0

0

Lipogranulomas

0

0

0

0

0

Portal inflammation

0

0

0

0

0

Cellular features

     

Hepatocytes hypertrophy/ Balloning

0

0

1

0

0

Acidophilic bodies

0

0

0

0

0

Pigmented macrophages

0

0

0

0

0

Megamitochondria

0

0

0

0

0

Mallory’s hyaline

0

0

0

0

0

Glycogenated nuclei

0

0

0

0

0

NAS score

0

0

4

0

0

Fibrosis score

0

0

0

0

0

  1. NAS: NAFLD activity score; NAFLD: non-alcoholic fatty liver disease.