Fig. 4
From: Effects of anserine on oxidative stress and on cell barrier integrity in methylmalonic aciduria
Effect of anserine on 10 kDa transport. Transport capacity for 10 kDa dextran was within the same range for mut0 and control cells (upper panel). Metabolic stress by High Protein load (HP) or branched-chain amino acids (IV, 1 mM isoleucine, 3 mM valine) had no additional effect on transport. Treatment with anserine for 7 days did not alter transport capacity. Dots in the violin plots represent the mean value for one patient analyzed in three independent experiments, each performed with 5–9 technical replicates. Statistical analysis was performed by two-way ANOVA with Šídák’s multiple comparisons test. There is no significance between the groups.
