Fig. 2 | Scientific Reports

Fig. 2

From: Comprehensive characterization of the molecular feature of acetylation in colorectal cancer using integrated single-cell and bulk RNA sequencing

Fig. 2

Weight co-expression network and gene enrichment analysis. (A) Dendrogram showing the hierarchical clustering of TCGA samples. The heatmap at the bottom represents the acetylation scores of each sample. (B) Cluster dendrogram of the WGCNA analysis. (C) Selection of the optimal soft threshold power. (D) Module-trait heatmap showing that the green modules were closely related to the acetylation trait. (E) Volcano plot showing differential analysis results between TCGA samples and normal samples. (F) Venn plot showing the intersecting genes between the green modules and DEGs in bulk RNA-seq. (G) GO enrichment of the overlapping genes. (H) Univariate Cox regression analysis of 30 acetylation-related genes.

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