Fig. 1

Risk factors associated with weaning outcomes. Shows the results of the regression analyses for the risk factors associated with the different weaning categories. Weaning category 3a (successful weaning without non-invasive Ventilation [NIV]) is shown in the upper left quadrant, with lower weight, longer invasive mechanical ventilation (IMV) before admission and comorbidities being detrimental. Weaning category 3b (successful weaning with NIV) is shown in the upper right quadrant, with higher weight, COPD, younger age, shorter IMV before admission and pre-existing NIV favouring this outcome. Weaning category 3cI (failed weaning with continued IMV) is shown in the lower left quadrant with older age, longer IMV before admission, cause of IMV neuromuscular disease, and comorbidities restrictive thoracic disease and critical illness polyneuropathy as predicters. Weaning category 3cII (death) is shown in the lower right quadrant with lower weight lower weight, malignancy and renal insufficiency as the main predictors for this outcome.