Fig. 5 | Scientific Reports

Fig. 5

From: Melissa officinalis essential oil modulates oxidative balance, cholinergic activity, and cognitive performance in a scopolamine-induced zebrafish model: implications for neuroprotective strategies in cognitive disorders

Fig. 5

Effects of Melissa officinalis essential oil administration (MEO, 150 and 300 µL/L) on spatial memory and novelty-seeking behavior in the Y-maze test. Galantamine (GAL, 1 mg/L) was used as a positive control. (A) Representative trajectories of zebrafish in the Y-maze; (B) number of arm entries; (C) distance traveled (m); (D) turn angle (°); (E) number of line crossings; (F) spontaneous alternation percentage (%), and (G) time spent in the novel arm (s). For the Y-maze arms: A- start arm, B – the other arm, and C – novel arm. Data are presented as mean ± SEM (n = 10 per group). Statistical significance was determined by one-way ANOVA followed by Tukey’s post hoc test: *p < 0.05, **p < 0.01, and ****p < 0.0001.

Back to article page