Table 2 Prevalence of various risk factors and their association with long-term ventilation in the overall cohort, as well as separately for women and men.
Predictor | All | Female | Male | Difference | |||
---|---|---|---|---|---|---|---|
Prevalence [%] | OR (95% CI) | Prevalence [%] | OR (95% CI) | Prevalence [%] | OR (95% CI) | p-value | |
Baseline predictors | |||||||
Intercept | |||||||
Age [years] | 1.00 (0.99–1.00) | - | 0.99 (0.98–0.99) | - | 1.00 (1.00–1.00) | ||
Sex [female] | 0.91 (0.83–1.01) | - | - | - | - | ||
Nursing home accommodation | 3.4 | 0.65 (0.49–0.87) | 4.5 | 0.62 (0.91–2.16) | 2.7 | 0.66 (0.46–0.94) | < 0.001 |
Diagnosis | |||||||
Pre-existing medical conditions (in 365 days prior to the MV case) | |||||||
Dementia | 7.7 | 1.87 (1.25–2.78) | 8.2 | 1.40 (0.91–2.16) | 7.3 | 2.68 (1.44–5.01) | 0.2228 |
Thyroiditis | 1.2 | 0.88 (0.73–1.05) | 2.3 | 1.05 (0.81–1.37) | 0.4 | 0.84 (0.68–1.04) | < 0.001 |
Eating disorders | 0.5 | 2.2 (1.2–4.03) | 0.8 | 0.95 (0.46–1.98) | 1.1 | 3.16 (1.37–7.26) | 0.0015 |
Rheumatic mitral valve disease | 1.5 | 2.37 (1.68–3.33) | 2.3 | 2.74 (1.82–4.12) | 0.6 | 1.71 (1.08–2.72) | < 0.001 |
Pneumothorax | 0.6 | 2.24 (1.19–4.22) | 0.5 | 1.76 (0.73–4.25) | 0.9 | 1.94 (1.02–3.69) | 0.8761 |
Peritonitis | 1.0 | 0.56 (0.32–0.96) | 1.2 | 0.70 (0.36–1.36) | 0.9 | 0.55 (0.3–1) | 0.1601 |
Admission diagnosis | |||||||
Cardiac arrhythmia | 0.9 | 0.66 (0.39–1.12) | 0.6 | 0.75 (0.29–1.93) | 1.2 | 0.89 (0.54–1.46) | 0.0012 |
Cerebral infarction | 2.9 | 2.08 (1.58–2.73) | 3.0 | 1.41 (0.97–2.07) | 2.8 | 2.33 (1.72–3.14) | 0.4503 |
Acute pancreatitis | 0.6 | 3.57 (2.02–6.3) | 0.3 | 4.73 (1.62–13.78) | 0.7 | 3.01 (1.69–5.37) | 0.0166 |
Diseases (previous diseases, admission diagnosis, MV case) | |||||||
Pulmonary or abdominal metastasis | 2.5 | 0.63 (0.45–0.88) | 2.4 | 0.67 (0.41–1.09) | 2.6 | 0.71 (0.5–1) | 0.6658 |
COPD | 30.7 | 1.85 (1.68–2.05) | 29.3 | 1.79 (1.54–2.08) | 31.5 | 1.73 (1.55–1.93) | 0.0118 |
Dependence on aspirator and/or ventilator (Non-invasive ventilation) | 5.0 | 6.1 (4.8–7.76) | 4.6 | 5.56 (3.97–7.77) | 5.2 | 6.19 (4.81–7.96) | 0.2251 |
Operations and procedures | |||||||
Operations and procedures in the 365 days prior to the MV case | |||||||
Tracheostomy. permanent or temporary | 3.3 | 2.53 (1.96–3.28) | 3.2 | 3.23 (2.24–4.66) | 3.3 | 2.73 (2.06–3.61) | 0.8068 |
Creation of a dialysis fistula. shunt or bypass | 0.8 | 0.34 (0.17–0.65) | 0.4 | 0.24 (0.05–1.13) | 1.0 | 0.49 (0.27–0.9) | < 0.001 |
Operations and procedures during theMV case up to 95 h after intubation | |||||||
Bronchoscopy | 35.1 | 1.15 (1.04–1.27) | 33.4 | 1.20 (1.03–1.38) | 36.1 | 1.15 (1.04–1.28) | 0.0029 |
Native computed tomography of the chest | 13.2 | 1.16 (1.01–1.33) | 12.5 | 1.16 (0.95–1.43) | 13.7 | 1.04 (0.9–1.21) | 0.0695 |
Computed tomography and/or magnetic resonance imaging of the cranium with imaging contrast medium | 10.7 | 1.34 (1.15–1.56) | 10.8 | 1.22 (0.99–1.52) | 10.7 | 1.31 (1.11–1.54) | 0.832 |
Operations on the spinal cerebrospinal fluid system (drainage. shunt. catheter; also. removal) | 0.4 | 2.54 (1.33–4.86) | 0.4 | 5.69 (1.92–16.83) | 0.5 | 2.01 (0.97–4.18) | 0.7901 |
Tracheostomy, permanent or temporary | 12.8 | 4.17 (3.63–4.78) | 12.5 | 4.44 (3.63–5.41) | 12.9 | 3.63 (3.12–4.22) | 0.5367 |
Radical cervical lymphadenectomy | 0.7 | 0.25 (0.13–0.5) | 0.6 | 0.09 (0.02–0.39) | 0.8 | 0.26 (0.13–0.51) | 0.4943 |
Chest tube | 10.8 | 1.35 (1.16–1.57) | 11.0 | 1.27 (1.03–1.58) | 10.6 | 1.23 (1.05–1.45) | 0.5556 |
Positioning treatment in a special bed** | 2.4 | 2.37 (1.78–3.15) | 2.2 | 2.07 (1.35–3.17) | 2.4 | 2.27 (1.66–3.13) | 0.5035 |
Autologous blood collection and transfusion | 2.7 | 0.71 (0.51–0.97) | 2.1 | 0.6 (0.35–1.01) | 3.0 | 0.83 (0.61–1.15) | 0.0064 |
Transfusion of plasma components and genetically engineered plasma proteins | 13.0 | 1.46 (1.27–1.69) | 12.4 | 1.4 (1.14–1.73) | 13.4 | 1.43 (1.22–1.66) | 0.1440 |
PECLA. ECCO2R. vv- und va ECMO und Pre-ECMO therapy | 3.4 | 1.43 (1.11–1.85) | 2.6 | 0.93 (0.6–1.42) | 3.9 | 1.62 (1.25–2.1) | < 0.001 |
Complex treatment for colonization or infection with multidrug-resistant pathogens | 6.1 | 1.46 (1.2–1.78) | 5.7 | 1.36 (1.03–1.81) | 6.4 | 1.44 (1.17–1.77) | 0.1166 |