Table 1 Regression parameters of the proposed HPLC method for the simultaneous determination of SAC and VAL in spiked human plasma.

From: A sensitive green HPLC-fluorescence method for simultaneous analysis of sacubitril and valsartan in pure forms, pharmaceutical dosage form and human plasma

Parameter

SAC

VAL

Range (µg/mL)

0.035–2.205

0.035–4.430

Slope

59.262

18.823

Intercept

− 0.0725

0.0935

r2

0.9993

0.9995

LOD(a) (µg/mL)

0.018

0.028

LOQ(b) (µg/mL)

0.053

0.085

  1. aLOD = (SD of the intercept /slope) × 3.3.
  2. bLOQ = (SD of the intercept /slope) × 10.
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