Table 3 Accuracy results of the proposed HPLC method for SAC and VAL in spiked human plasma.

From: A sensitive green HPLC-fluorescence method for simultaneous analysis of sacubitril and valsartan in pure forms, pharmaceutical dosage form and human plasma

Concentration (µg/mL)

Recovery %* (Mean ± SD)

SAC

VAL

0.35

98.42 + 0.56

98.84 + 0.60

0.44

101.25 + 0.32

101.62 + 0.38

1.32

100.92 + 0.36

100.54 + 0.94

1.77

99.08 + 0.51

100.52 + 0.91

2.22

101.22 + 0.58

100.47 + 0.55

Mean ± SD

100.18 ± 1.33

100.40 ± 1.00

  1. *Average of 3 determinations.
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