Table 7 Statistical comparison of the results obtained by applying the proposed HPLC method and the reported one13 in spiked human plasma, for determination of SAC and VAL in (a) their pure forms, and in (b) pharmaceutical dosage forms.
Parameter | SAC | VAL | ||
|---|---|---|---|---|
Proposed method | Reported method* | Proposed method | Reported method* | |
(a) | ||||
Mean | 100.18 | 100.10 | 100.40 | 99.24 |
SD | 1.33 | 0.91 | 1.00 | 0.48 |
Variance | 1.77 | 0.83 | 1.00 | 0.23 |
n | 5 | 5 | 5 | 5 |
Student’s t-test (2.306)** | 0.103 | 1.642 | ||
F value (5.32)** | 2.12 | 4.34 | ||
(b) | ||||
Mean | 101.46 | 101.08 | 102.84 | 100.59 |
SD | 0.18 | 0.36 | 0.91 | 1.67 |
Variance | 0.03 | 0.13 | 0.83 | 2.79 |
n | 3 | 3 | 3 | 3 |
Student’s t-test (2.776)** | 1.744 | 2.045 | ||
F value (7.71)** | 3.85 | 3.37 | ||
