Fig. 3 | Scientific Reports

Fig. 3

From: Longitudinal trajectories unravel the complex interplay of medication, cardiovascular events, chronic kidney disease, and mortality

Fig. 3

Comparison of trajectories of new users of PPI or H2B, 2006–2021. Trajectories: Chronological disease trajectories including Medication, CKD outcomes, CVAE, Death/Study end; each trajectory is presented with the relative frequency, absolute frequency and cumulative frequency. Trajectories are ordered by frequency. PPI vs. H2B for the following trajectory: hazard ratios and 95% confidence intervals of undergoing a specific trajectory between PPI and H2B users. Estimates were derived from a Cox proportional hazards model with inverse probability weighting (IPW), adjusting for age, sex, eGFR at index, comorbidities, and concomitant medication use at index.

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