Fig. 5 | Scientific Reports

Fig. 5

From: Comparison of in vitro migration assays evaluating nintedanib’s migration inhibitory effects on melanoma cells

Fig. 5

Evaluating nintedanib effect on cell migration by gap closure assays. Relative scratch (A) and Z-E (B) areas were normalized to the initial gap size at t = 0 and tracked over time. Corresponding AUC values are shown for each cell line in the presence of 1 or 2 µM nintedanib. Data are shown as mean ± 95% CI, based on N = 24 replicates for scratch and N = 12 for Z-E across four independent experiment. Replicates falling outside ± 2 SD were excluded as outliers. Statistical analysis was performed using the Kruskal–Wallis test; p < 0.05 was considered statistically significant.

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