Fig. 3 | Scientific Reports

Fig. 3

From: Chromatin and transcriptional dynamics underlying the immune-modulatory effects of vitamin D3 in vivo

Fig. 3

Integration of epigenomic and transcriptomic profiles. The relationship between changes in chromatin accessibility (log2FC, shown for d1 versus d0) of 712 vitamin D sensitive chromatin regions and corresponding changes in the expression of 306 target genes is plotted. Data are shown for 108 TSS regions directly associated with vitamin D target genes (A), TSS regions (n = 424) linked to non-target genes (B), 94 proximal enhancer regions (C) and 82 distal enhancers (D). Chromatin regions overlapping with a VDR binding site (red) are distinguished from those not known to bind VDR.

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