Fig. 5 | Scientific Reports

Fig. 5

From: Chromatin and transcriptional dynamics underlying the immune-modulatory effects of vitamin D3 in vivo

Fig. 5

Comparing cohort and N-of-1 approaches. Venn diagrams compare the cohort and N-of-1 approach for all consensus peaks (A) and significantly regulated peaks (B). Representative genomic regions of vitamin D–responsive chromatin accessibility for the target genes NR4A1 (C) and RBM38 (D), visualized in the IGV browser. Enhancer and TSS regions are shaded in light grey, with vitamin D target genes highlighted in red. Tracks display merged ATAC-seq data from 13 individuals in the VitDPAS trial (d0, d1) and from three biological replicates in the N-of-1 approach (d0, d1, d2).

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