Table 2 Potential transcriptional and post-transcription regulatory biomolecules of ID.
TFs | Description | Function |
|---|---|---|
Transcriptional regulatory biomolecules (TFs) | ||
 FOXC1 | Forkhead box | The activity of DNA-binding transcription factors and the specificity of RNA polymerase II. |
 GATA2 | GATA binding protein 2 | The activity of transcription factors that bind to DNA and their association with chromatin. |
 FOXL1 | Forkhead box L1 | The transcription factor is essential for the appropriate proliferation and differentiation processes within the gastrointestinal epithelium. |
 TFAP2C | Transcription Factor AP-2 Gamma | A DNA-binding protein with sequence specificity that engages with inducible viral and cellular enhancer elements. |
 NR3C1 | Nuclear Receptor Subfamily 3 Group C Member 1 | Aids in the degradation of messenger RNAs (mRNAs) quickly by binding to their 5’ untranslated regions (UTRs). |
 HINFP | Histone H4 Transcription Factor | The transcriptional repressor exhibits binding affinity to the consensus sequence 5’-CGGACGTT-3’ as to well as the RB1 promoter. |
 SREBF1 | Sterol Regulatory Element Binding Transcription Factor 1 | The precursor of the transcription factor form, known as processed sterol regulatory element binding protein 1 (SREBP-1) is localized within the membrane of the endoplasmic reticulum. |
miRNAs | Description | Function |
|---|---|---|
Post-transcription regulatory biomolecules (miRNAs) | ||
 mir-16- 5p | MicroRNA 16 | Prevent replication of multiple viruses (EV71). |
 mir-193b-3p | MicroRNA 193b | Demonstrates reciprocal interaction with MYC and inhibits the growth and metastasis. |
 mir-93-5p | MicroRNA 93 | Contributes to the genesis of different diseases. |
 mir-92a-3p | MicroRNA 92a | Reduces PTEN and prevents Eca-109 cells from being phosphorylated and inhibited by Akt. |
 mir-186-5p | MicroRNA186 | Inhibit tumorigenesis of glioblastoma multiforme both in vitro and in vivo. |
