Table 1 Baseline characteristics of high risk NDMM patients.

From: VRd vs. VPd as induction therapy in high risk newly diagnosed multiple myeloma

Characteristics

VRd (n = 25)

VPd(n = 21)

p value

Follow-up time, m(range)

< 12

≥ 12

18(72)

7(28)

16(76.2)

5(23.8)

0.747

Medina age, y(range)

64(50–81)

69(51–80)

0.218

Male, n (%)

10(40)

12(57.1)

0.245

Myeloma type, n (%)

IgG/IgA

Light chain only

22(88)

3(12)

20(95.2)

1(4.8)

0.373

Creatinine Level, µmol/L(range)

69(28–320)

85(35–770)

0.055

β2-MG, mg/L(range)

7.15(3.03–14.39)

7.59(5.50-71.62)

0.109

DS

I-II

III

2(8)

23(92)

3(14.3)

18(85.7)

0.496

ISS

I-II

III

1(4)

24(96)

0

21(100)

0.266

R-ISS

I-II

III

1(4)

24(96)

1(4.8)

20(95.2)

0.9

Chromosome

Complex karyotype

Normal

4(16)

21(84)

4 (19)

17(81)

0.786

FISH

Normal

Abnormal

1(4)

24(96)

1(4.8)

20(95.2)

0.9

EMD

No

Yes

24(96)

1(4)

19(90.5)

2(9.5)

0.449

ASCT

Yes

No

6(24)

19(76)

1(4.8)

20(95.2)

0.056

  1. Data are expressed in terms of median (IQR) for continuous variables and n (%) for categorical values.
  2. DS, Durie-Salmon; ISS, International-Staging-System; R-ISS, Revised-International-Staging-System; FISH Abnormal,17p deletion, t (4;14), t (14;20), t (14;16), EMD, myeloid external disease; ASCT, autologous stem cell transplantation.