Fig. 1

LIRA improved the disorders of glycol-metabolism in db/db mice. (A) The schematic diagram of the experimental flow. (B) The blood glucose of mice from the 9th to 15th week. (The data are shown as the means ± SEM. n = 6. **p < 0.01 vs. db/m group. ^##p < 0.01 vs. db/db group. ^$$p < 0.01 vs. db/db group 9th week. ^&p < 0.05, ^&&p < 0.01 vs. LIRA group 9th week). (C) The intraperitoneal glucose tolerance test of mice with 120 min. (D) The HOMA-insulin resistance (HOMA-IR) of db/m, db/db and LIRA groups. (E–F) The diastolic and systolic pressure. (G) The triglyceride (TG) and cholesterol (CHO) levels in serum. (H–I) The ratio of LKW/BW and the left kidney weight of mice in each group. (J–M) The albumin, BUN, Scr, beta-2 microglobulin (beta 2-MG), and n-acetyl-β-D-glucosidase (NAG) content in serum of mice in different groups. The data are shown as the means ± SEM. n = 6. **p < 0.05 vs. db/m group. ^##p < 0.01 vs. db/db group).