Fig. 5
From: Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway
The ferroptosis in kidney tissue of db/db mice. (A) The ultrastructure of mitochondria observed by TEM. (B–C) The activity of GSH and GSH-Px in the kidney tissue (n = 5). (D) The expression and statistics of GPX-4 and Fsp1 proteins (n = 6). (E) The immunohistochemical staining of GPX-4 protein (scale bar = 100 μm, n = 3). (F–G) The ratio of NAD+/NADH and CoQ10 (H2)/CoQ10 (n = 4). The results are presented as the mean ± SEM. *p < 0.05, **p < 0.01 vs. db/m group. #p < 0.05, ##p < 0.01 vs. db/db group.
