Fig. 9 | Scientific Reports

Fig. 9

From: Integrative analysis of single-cell and transcriptome sequencing with experimental validation reveals PKHD1L1 as a novel biomarker in lung adenocarcinoma

Fig. 9

The over-expression of PKHD1L1 significantly inhibited the proliferation and migration of LUAD cell lines. (A–D) CCK8 and colony formation assays were performed on H1299 and A549 cells with and without PKHD1L1 over-expression. These experiments were designed to determine the effect of PKHD1L1 on the proliferation of these LUAD cell lines. (E–H) In addition, we assessed the effect of PKHD1L1 on the migratory capacity of both the control and PKHD1L1-overexpressing cell lines via wound healing and migration assays (*p < 0.05, ** p < 0.01, *** p < 0.00).

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